Penicillin Allergy Skin Testing in the Inpatient Setting

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Utility of minor determinants in penicillin allergy skin testing

Background Penicillin allergy is a major concern among patients and physicians. There’s an estimated 5-10% self reported history of penicillin allergy by patients, but vast majority are not true hypersensitivities. Complete penicillin skin test with both major, minor determinants and amoxicillin is the test of choice for diagnosing IgE-mediated penicillin allergy. While Penicilloyl polylysine (...

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Routine Penicillin Skin Testing in Hospitalized Patients with a History of Penicillin Allergy.

BACKGROUND In selected inpatient settings, penicillin skin testing has been shown to affect antibiotic use. Routine penicillin skin testing has not been studied in hospitalized patients with a history of penicillin allergy. OBJECTIVES To determine whether routine penicillin skin testing at a large regional hospital affected antibiotic use and/or antibiotic side effects in hospitalized persons...

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Skin testing only with penicillin G in children with a history of penicillin allergy.

BACKGROUND The absence of commercially available penicilloyl-polylysine (PPL) for most of the last decade severely hampered the practice of penicillin allergy evaluation because skin testing without PPL is reported to have a poor negative predictive value (NPV). OBJECTIVE To determine the safety and NPV of skin testing without PPL using only penicillin G followed by a 3-dose graded challenge ...

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Utility of penicillin allergy testing in patients presenting with a history of penicillin allergy

BACKGROUND Current statistics show that approximately 10% of patients claim to be allergic to penicillin yet only 10% of these have demonstrable allergy. The most appropriate and cost-effective antibiotics are sometimes withheld on the basis of patient history of drug allergy. OBJECTIVE Investigation of IgE hypersensitivity and delayed hypersensitivity in patients with a history of penicillin...

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Penicillin Allergy Testing Should Be Performed Routinely in Patients with Self-Reported Penicillin Allergy.

h AAAAI Position Statements, Work Group Reports, and Systematic Reviews are not to be considered to reflect current AAAAI standards or policy after five years from the date of publication. The statement below is not to be construed as dictating an exclusive course of action nor is it intended to replace the medical judgment of healthcare professionals. The unique circumstances of individual pat...

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ژورنال

عنوان ژورنال: Pharmacy

سال: 2019

ISSN: 2226-4787

DOI: 10.3390/pharmacy7030120